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Intracardiac Thrombus Formation and Bilateral Pulmonary Embolisms in a Patient With Behcet's Disease While on Regular Infliximab Infusion: A Case Report

Vascular complications of Behcet'sdisease, including intracardiac thrombus formation, are one of the significant causes of mortality and morbidity in this population. Similar to other vasculitic disorders, Behcet's disease is primarily treated with immunosuppressants. While the benefit of...

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Autores principales: Miqdad, Mohammed A, Mohamad, Abdullah, Ali, Fawaz, Kawari, Mohammed, Alboainain, Salha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575333/
https://www.ncbi.nlm.nih.gov/pubmed/34765357
http://dx.doi.org/10.7759/cureus.18592
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author Miqdad, Mohammed A
Mohamad, Abdullah
Ali, Fawaz
Kawari, Mohammed
Alboainain, Salha
author_facet Miqdad, Mohammed A
Mohamad, Abdullah
Ali, Fawaz
Kawari, Mohammed
Alboainain, Salha
author_sort Miqdad, Mohammed A
collection PubMed
description Vascular complications of Behcet'sdisease, including intracardiac thrombus formation, are one of the significant causes of mortality and morbidity in this population. Similar to other vasculitic disorders, Behcet's disease is primarily treated with immunosuppressants. While the benefit of adding anticoagulants in Behcet's disease with thromboembolism remains debatable, some literature encourages its use with concomitant intracardiac thrombus. Herewith, we present the case of a young male who was diagnosed with bilateral pulmonary embolism in addition to right ventricle intracardiac thrombus upon his scheduled dose of infliximab infusion. He was managed by adding azathioprine to his regimen together with oral prednisolone and warfarin with a target international normalized ratio of 2-3. This case report addresses the importance and outcome of early identification of Behcet's disease's vascular complications and immediate initiation of anticoagulation accordingly.
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spelling pubmed-85753332021-11-10 Intracardiac Thrombus Formation and Bilateral Pulmonary Embolisms in a Patient With Behcet's Disease While on Regular Infliximab Infusion: A Case Report Miqdad, Mohammed A Mohamad, Abdullah Ali, Fawaz Kawari, Mohammed Alboainain, Salha Cureus Cardiology Vascular complications of Behcet'sdisease, including intracardiac thrombus formation, are one of the significant causes of mortality and morbidity in this population. Similar to other vasculitic disorders, Behcet's disease is primarily treated with immunosuppressants. While the benefit of adding anticoagulants in Behcet's disease with thromboembolism remains debatable, some literature encourages its use with concomitant intracardiac thrombus. Herewith, we present the case of a young male who was diagnosed with bilateral pulmonary embolism in addition to right ventricle intracardiac thrombus upon his scheduled dose of infliximab infusion. He was managed by adding azathioprine to his regimen together with oral prednisolone and warfarin with a target international normalized ratio of 2-3. This case report addresses the importance and outcome of early identification of Behcet's disease's vascular complications and immediate initiation of anticoagulation accordingly. Cureus 2021-10-08 /pmc/articles/PMC8575333/ /pubmed/34765357 http://dx.doi.org/10.7759/cureus.18592 Text en Copyright © 2021, Miqdad et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Miqdad, Mohammed A
Mohamad, Abdullah
Ali, Fawaz
Kawari, Mohammed
Alboainain, Salha
Intracardiac Thrombus Formation and Bilateral Pulmonary Embolisms in a Patient With Behcet's Disease While on Regular Infliximab Infusion: A Case Report
title Intracardiac Thrombus Formation and Bilateral Pulmonary Embolisms in a Patient With Behcet's Disease While on Regular Infliximab Infusion: A Case Report
title_full Intracardiac Thrombus Formation and Bilateral Pulmonary Embolisms in a Patient With Behcet's Disease While on Regular Infliximab Infusion: A Case Report
title_fullStr Intracardiac Thrombus Formation and Bilateral Pulmonary Embolisms in a Patient With Behcet's Disease While on Regular Infliximab Infusion: A Case Report
title_full_unstemmed Intracardiac Thrombus Formation and Bilateral Pulmonary Embolisms in a Patient With Behcet's Disease While on Regular Infliximab Infusion: A Case Report
title_short Intracardiac Thrombus Formation and Bilateral Pulmonary Embolisms in a Patient With Behcet's Disease While on Regular Infliximab Infusion: A Case Report
title_sort intracardiac thrombus formation and bilateral pulmonary embolisms in a patient with behcet's disease while on regular infliximab infusion: a case report
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575333/
https://www.ncbi.nlm.nih.gov/pubmed/34765357
http://dx.doi.org/10.7759/cureus.18592
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