Cargando…
Intracardiac Thrombus Formation and Bilateral Pulmonary Embolisms in a Patient With Behcet's Disease While on Regular Infliximab Infusion: A Case Report
Vascular complications of Behcet'sdisease, including intracardiac thrombus formation, are one of the significant causes of mortality and morbidity in this population. Similar to other vasculitic disorders, Behcet's disease is primarily treated with immunosuppressants. While the benefit of...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575333/ https://www.ncbi.nlm.nih.gov/pubmed/34765357 http://dx.doi.org/10.7759/cureus.18592 |
_version_ | 1784595658745839616 |
---|---|
author | Miqdad, Mohammed A Mohamad, Abdullah Ali, Fawaz Kawari, Mohammed Alboainain, Salha |
author_facet | Miqdad, Mohammed A Mohamad, Abdullah Ali, Fawaz Kawari, Mohammed Alboainain, Salha |
author_sort | Miqdad, Mohammed A |
collection | PubMed |
description | Vascular complications of Behcet'sdisease, including intracardiac thrombus formation, are one of the significant causes of mortality and morbidity in this population. Similar to other vasculitic disorders, Behcet's disease is primarily treated with immunosuppressants. While the benefit of adding anticoagulants in Behcet's disease with thromboembolism remains debatable, some literature encourages its use with concomitant intracardiac thrombus. Herewith, we present the case of a young male who was diagnosed with bilateral pulmonary embolism in addition to right ventricle intracardiac thrombus upon his scheduled dose of infliximab infusion. He was managed by adding azathioprine to his regimen together with oral prednisolone and warfarin with a target international normalized ratio of 2-3. This case report addresses the importance and outcome of early identification of Behcet's disease's vascular complications and immediate initiation of anticoagulation accordingly. |
format | Online Article Text |
id | pubmed-8575333 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-85753332021-11-10 Intracardiac Thrombus Formation and Bilateral Pulmonary Embolisms in a Patient With Behcet's Disease While on Regular Infliximab Infusion: A Case Report Miqdad, Mohammed A Mohamad, Abdullah Ali, Fawaz Kawari, Mohammed Alboainain, Salha Cureus Cardiology Vascular complications of Behcet'sdisease, including intracardiac thrombus formation, are one of the significant causes of mortality and morbidity in this population. Similar to other vasculitic disorders, Behcet's disease is primarily treated with immunosuppressants. While the benefit of adding anticoagulants in Behcet's disease with thromboembolism remains debatable, some literature encourages its use with concomitant intracardiac thrombus. Herewith, we present the case of a young male who was diagnosed with bilateral pulmonary embolism in addition to right ventricle intracardiac thrombus upon his scheduled dose of infliximab infusion. He was managed by adding azathioprine to his regimen together with oral prednisolone and warfarin with a target international normalized ratio of 2-3. This case report addresses the importance and outcome of early identification of Behcet's disease's vascular complications and immediate initiation of anticoagulation accordingly. Cureus 2021-10-08 /pmc/articles/PMC8575333/ /pubmed/34765357 http://dx.doi.org/10.7759/cureus.18592 Text en Copyright © 2021, Miqdad et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Cardiology Miqdad, Mohammed A Mohamad, Abdullah Ali, Fawaz Kawari, Mohammed Alboainain, Salha Intracardiac Thrombus Formation and Bilateral Pulmonary Embolisms in a Patient With Behcet's Disease While on Regular Infliximab Infusion: A Case Report |
title | Intracardiac Thrombus Formation and Bilateral Pulmonary Embolisms in a Patient With Behcet's Disease While on Regular Infliximab Infusion: A Case Report |
title_full | Intracardiac Thrombus Formation and Bilateral Pulmonary Embolisms in a Patient With Behcet's Disease While on Regular Infliximab Infusion: A Case Report |
title_fullStr | Intracardiac Thrombus Formation and Bilateral Pulmonary Embolisms in a Patient With Behcet's Disease While on Regular Infliximab Infusion: A Case Report |
title_full_unstemmed | Intracardiac Thrombus Formation and Bilateral Pulmonary Embolisms in a Patient With Behcet's Disease While on Regular Infliximab Infusion: A Case Report |
title_short | Intracardiac Thrombus Formation and Bilateral Pulmonary Embolisms in a Patient With Behcet's Disease While on Regular Infliximab Infusion: A Case Report |
title_sort | intracardiac thrombus formation and bilateral pulmonary embolisms in a patient with behcet's disease while on regular infliximab infusion: a case report |
topic | Cardiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575333/ https://www.ncbi.nlm.nih.gov/pubmed/34765357 http://dx.doi.org/10.7759/cureus.18592 |
work_keys_str_mv | AT miqdadmohammeda intracardiacthrombusformationandbilateralpulmonaryembolismsinapatientwithbehcetsdiseasewhileonregularinfliximabinfusionacasereport AT mohamadabdullah intracardiacthrombusformationandbilateralpulmonaryembolismsinapatientwithbehcetsdiseasewhileonregularinfliximabinfusionacasereport AT alifawaz intracardiacthrombusformationandbilateralpulmonaryembolismsinapatientwithbehcetsdiseasewhileonregularinfliximabinfusionacasereport AT kawarimohammed intracardiacthrombusformationandbilateralpulmonaryembolismsinapatientwithbehcetsdiseasewhileonregularinfliximabinfusionacasereport AT alboainainsalha intracardiacthrombusformationandbilateralpulmonaryembolismsinapatientwithbehcetsdiseasewhileonregularinfliximabinfusionacasereport |