Ruxolitinib-Associated Phaeohyphomycosis: A Case Report

We present the findings of a rare fungal infection phaeohyphomycosis caused by Pleurostoma richardsiae (P. richardsiae) in an immunocompromised 82-year-old male with myelodysplastic syndrome on treatment with the Janus kinase inhibitor ruxolitinib. Hematologists, infectious disease physicians, and s...

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Detalles Bibliográficos
Autores principales: Marples, Rory, Micallef, Milton, Whyte, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
General Surgery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575341/
https://www.ncbi.nlm.nih.gov/pubmed/34765385
http://dx.doi.org/10.7759/cureus.19335
Descripción
Sumario:We present the findings of a rare fungal infection phaeohyphomycosis caused by Pleurostoma richardsiae (P. richardsiae) in an immunocompromised 82-year-old male with myelodysplastic syndrome on treatment with the Janus kinase inhibitor ruxolitinib. Hematologists, infectious disease physicians, and surgeons should consider a fungal etiology in cases of cellulitis refractory to standard treatments in those patients with underlying immune dysfunction and/or in those receiving therapy with ruxolitinib or similar agents.

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