Detection of MSH2 Gene Methylation in Extramammary Paget's Disease by Methylation-Sensitive High-Resolution Melting Analysis

BACKGROUND: Extramammary Paget's disease (EMPD) is a rare skin tumor. Hypermethylation in the MSH2 promoter resulting in the downregulation of its protein expression shows a high detection rate in EMPD tumor tissue, which indicates that the methylation of MSH2 may play an important role in the...

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Detalles Bibliográficos
Autores principales: Dong, Liu, Zhu, Yingfeng, Wu, Liting, Zhang, Qiaoan, Xu, Feng, Zhang, Xinju, Xu, Xiao, Tang, Yiting, Ren, Guoqiang, Kang, Zhihua, Guan, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575627/
https://www.ncbi.nlm.nih.gov/pubmed/34759969
http://dx.doi.org/10.1155/2021/5514426

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