Structural basis of the interaction between SETD2 methyltransferase and hnRNP L paralogs for governing co-transcriptional splicing

The RNA recognition motif (RRM) binds to nucleic acids as well as proteins. More than one such domain is found in the pre-mRNA processing hnRNP proteins. While the mode of RNA recognition by RRMs is known, the molecular basis of their protein interaction remains obscure. Here we describe the mode of...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Saikat, Wang, Suman, Reddy, Divya, Shen, Siyuan, Zhang, Ying, Zhang, Ning, Li, Hua, Washburn, Michael P., Florens, Laurence, Shi, Yunyu, Workman, Jerry L., Li, Fudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575775/
https://www.ncbi.nlm.nih.gov/pubmed/34750379
http://dx.doi.org/10.1038/s41467-021-26799-3

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