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Validation of the accuracy of the childhood asthma model for clinical decision support: a study protocol

BACKGROUND: In China, the average prevalence of asthma in children aged 0–14 years increased by approximately 50% every 10 years. Hence, a specific decision support system that fits China’s situation is needed for childhood asthma. This prospective, multicenter, observational study aims to assess th...

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Autores principales: Dong, Na, Wu, Beirong, Yin, Bingru, Dong, Wei, Jin, Xiaoqun, Wang, Miao, Xu, Xiuhe, Zhi, Canghong, Zhao, Dandan, Lu, Min, Gu, Haoxiang, Qiao, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575833/
https://www.ncbi.nlm.nih.gov/pubmed/34795951
http://dx.doi.org/10.21037/jtd-21-668
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author Dong, Na
Wu, Beirong
Yin, Bingru
Dong, Wei
Jin, Xiaoqun
Wang, Miao
Xu, Xiuhe
Zhi, Canghong
Zhao, Dandan
Lu, Min
Gu, Haoxiang
Qiao, Rong
author_facet Dong, Na
Wu, Beirong
Yin, Bingru
Dong, Wei
Jin, Xiaoqun
Wang, Miao
Xu, Xiuhe
Zhi, Canghong
Zhao, Dandan
Lu, Min
Gu, Haoxiang
Qiao, Rong
author_sort Dong, Na
collection PubMed
description BACKGROUND: In China, the average prevalence of asthma in children aged 0–14 years increased by approximately 50% every 10 years. Hence, a specific decision support system that fits China’s situation is needed for childhood asthma. This prospective, multicenter, observational study aims to assess the accuracy of the Childhood Asthma Model for Clinical Decision Support (CAMCDS) in clinical practice in four hospitals in Shanghai in China. METHODS: The study will be conducted in two phases. Phase I of the study aims to evaluate the accuracy of the CAMCDS for diagnosis, while phase II of the study aims to examine the treatment predicting accuracy of the CAMCDS model. In total, 817 children diagnosed with stable asthma and 545 suspected asthma will be enrolled. The accuracy of the CAMCDS model will be calculated using the receiver operating characteristic (ROC) curve compared with the results of pediatrician’s diagnosis. Besides, the treatment patterns from CAMCDS and real-world environment for Chinese children with stable asthma will be assessed, and the factors that affect the CAMCDS implementation in routine clinical practice will be explored. CONCLUSIONS: This will be the first study to examine the diagnostic accuracy and treatment predicting accuracy of a clinical decision support system in children with asthma in China. We hope that the CAMCDS will be help pediatricians in basic-level hospitals to improve the diagnosis and treatment strategy of asthma. TRIAL REGISTRATION: Chinese Clinical Trial Registry Identifier: ChiCTR2100045283.
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spelling pubmed-85758332021-11-17 Validation of the accuracy of the childhood asthma model for clinical decision support: a study protocol Dong, Na Wu, Beirong Yin, Bingru Dong, Wei Jin, Xiaoqun Wang, Miao Xu, Xiuhe Zhi, Canghong Zhao, Dandan Lu, Min Gu, Haoxiang Qiao, Rong J Thorac Dis Study Protocol BACKGROUND: In China, the average prevalence of asthma in children aged 0–14 years increased by approximately 50% every 10 years. Hence, a specific decision support system that fits China’s situation is needed for childhood asthma. This prospective, multicenter, observational study aims to assess the accuracy of the Childhood Asthma Model for Clinical Decision Support (CAMCDS) in clinical practice in four hospitals in Shanghai in China. METHODS: The study will be conducted in two phases. Phase I of the study aims to evaluate the accuracy of the CAMCDS for diagnosis, while phase II of the study aims to examine the treatment predicting accuracy of the CAMCDS model. In total, 817 children diagnosed with stable asthma and 545 suspected asthma will be enrolled. The accuracy of the CAMCDS model will be calculated using the receiver operating characteristic (ROC) curve compared with the results of pediatrician’s diagnosis. Besides, the treatment patterns from CAMCDS and real-world environment for Chinese children with stable asthma will be assessed, and the factors that affect the CAMCDS implementation in routine clinical practice will be explored. CONCLUSIONS: This will be the first study to examine the diagnostic accuracy and treatment predicting accuracy of a clinical decision support system in children with asthma in China. We hope that the CAMCDS will be help pediatricians in basic-level hospitals to improve the diagnosis and treatment strategy of asthma. TRIAL REGISTRATION: Chinese Clinical Trial Registry Identifier: ChiCTR2100045283. AME Publishing Company 2021-10 /pmc/articles/PMC8575833/ /pubmed/34795951 http://dx.doi.org/10.21037/jtd-21-668 Text en 2021 Journal of Thoracic Disease. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Study Protocol
Dong, Na
Wu, Beirong
Yin, Bingru
Dong, Wei
Jin, Xiaoqun
Wang, Miao
Xu, Xiuhe
Zhi, Canghong
Zhao, Dandan
Lu, Min
Gu, Haoxiang
Qiao, Rong
Validation of the accuracy of the childhood asthma model for clinical decision support: a study protocol
title Validation of the accuracy of the childhood asthma model for clinical decision support: a study protocol
title_full Validation of the accuracy of the childhood asthma model for clinical decision support: a study protocol
title_fullStr Validation of the accuracy of the childhood asthma model for clinical decision support: a study protocol
title_full_unstemmed Validation of the accuracy of the childhood asthma model for clinical decision support: a study protocol
title_short Validation of the accuracy of the childhood asthma model for clinical decision support: a study protocol
title_sort validation of the accuracy of the childhood asthma model for clinical decision support: a study protocol
topic Study Protocol
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575833/
https://www.ncbi.nlm.nih.gov/pubmed/34795951
http://dx.doi.org/10.21037/jtd-21-668
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