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Osteocrin ameliorates adriamycin nephropathy via p38 mitogen-activated protein kinase inhibition

Natriuretic peptides exert multiple effects by binding to natriuretic peptide receptors (NPRs). Osteocrin (OSTN) binds with high affinity to NPR-C, a clearance receptor for natriuretic peptides, and inhibits degradation of natriuretic peptides and consequently enhances guanylyl cyclase-A (GC-A/NPR1)...

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Detalles Bibliográficos
Autores principales:	Handa, Takaya, Mori, Keita P., Ishii, Akira, Ohno, Shoko, Kanai, Yugo, Watanabe-Takano, Haruko, Yasoda, Akihiro, Kuwabara, Takashige, Takahashi, Nobuyuki, Mochizuki, Naoki, Mukoyama, Masashi, Yanagita, Motoko, Yokoi, Hideki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575949/ https://www.ncbi.nlm.nih.gov/pubmed/34750411 http://dx.doi.org/10.1038/s41598-021-01095-8

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