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Estimating disease prevalence in large datasets using genetic risk scores
Clinical classification is essential for estimating disease prevalence but is difficult, often requiring complex investigations. The widespread availability of population level genetic data makes novel genetic stratification techniques a highly attractive alternative. We propose a generalizable math...
Autores principales: | Evans, Benjamin D., Słowiński, Piotr, Hattersley, Andrew T., Jones, Samuel E., Sharp, Seth, Kimmitt, Robert A., Weedon, Michael N., Oram, Richard A., Tsaneva-Atanasova, Krasimira, Thomas, Nicholas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575951/ https://www.ncbi.nlm.nih.gov/pubmed/34750397 http://dx.doi.org/10.1038/s41467-021-26501-7 |
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