Extracellular vesicles released by human retinal pigment epithelium mediate increased polarised secretion of drusen proteins in response to AMD stressors

Age‐related macular degeneration (AMD) is a leading cause of blindness worldwide. Drusen are key contributors to the etiology of AMD and the ability to modulate drusen biogenesis could lead to therapeutic strategies to slow or halt AMD progression. The mechanisms underlying drusen biogenesis, howeve...

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Detalles Bibliográficos
Autores principales: Flores‐Bellver, Miguel, Mighty, Jason, Aparicio‐Domingo, Silvia, Li, Kang V., Shi, Cui, Zhou, Jing, Cobb, Hannah, McGrath, Patrick, Michelis, German, Lenhart, Patricia, Bilousova, Ganna, Heissel, Søren, Rudy, Michael J., Coughlan, Christina, Goodspeed, Andrew E., Becerra, S. Patricia, Redenti, Stephen, Canto‐Soler, M. Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575963/
https://www.ncbi.nlm.nih.gov/pubmed/34750957
http://dx.doi.org/10.1002/jev2.12165

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