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Near-Infrared Inorganic Nanomaterials for Precise Diagnosis and Therapy

Traditional wavelengths (400–700 nm) have made tremendous inroads in vivo fluorescence imaging. However, the ability of visible light photon penetration hampered the bio-applications. With reduced photon scattering, minimal tissue absorption and negligible autofluorescence properties, near-infrared...

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Detalles Bibliográficos
Autores principales: Li, Wenling, Zhang, Guilong, Liu, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576183/
https://www.ncbi.nlm.nih.gov/pubmed/34765596
http://dx.doi.org/10.3389/fbioe.2021.768927
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author Li, Wenling
Zhang, Guilong
Liu, Lu
author_facet Li, Wenling
Zhang, Guilong
Liu, Lu
author_sort Li, Wenling
collection PubMed
description Traditional wavelengths (400–700 nm) have made tremendous inroads in vivo fluorescence imaging. However, the ability of visible light photon penetration hampered the bio-applications. With reduced photon scattering, minimal tissue absorption and negligible autofluorescence properties, near-infrared light (NIR 700–1700 nm) demonstrates better resolution, high signal-to-background ratios, and deep tissue penetration capability, which will be of great significance for in-vivo determination in deep tissue. In this review, we summarized the latest novel NIR inorganic nanomaterials and the emission mechanism including single-walled carbon nanotubes, rare-earth nanoparticles, quantum dots, metal nanomaterials. Subsequently, the recent progress of precise noninvasive diagnosis in biomedicine and cancer therapy utilizing near-infrared inorganic nanomaterials are discussed. In addition, this review will highlight the concerns, challenges and future directions of near-infrared light utilization.
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spelling pubmed-85761832021-11-10 Near-Infrared Inorganic Nanomaterials for Precise Diagnosis and Therapy Li, Wenling Zhang, Guilong Liu, Lu Front Bioeng Biotechnol Bioengineering and Biotechnology Traditional wavelengths (400–700 nm) have made tremendous inroads in vivo fluorescence imaging. However, the ability of visible light photon penetration hampered the bio-applications. With reduced photon scattering, minimal tissue absorption and negligible autofluorescence properties, near-infrared light (NIR 700–1700 nm) demonstrates better resolution, high signal-to-background ratios, and deep tissue penetration capability, which will be of great significance for in-vivo determination in deep tissue. In this review, we summarized the latest novel NIR inorganic nanomaterials and the emission mechanism including single-walled carbon nanotubes, rare-earth nanoparticles, quantum dots, metal nanomaterials. Subsequently, the recent progress of precise noninvasive diagnosis in biomedicine and cancer therapy utilizing near-infrared inorganic nanomaterials are discussed. In addition, this review will highlight the concerns, challenges and future directions of near-infrared light utilization. Frontiers Media S.A. 2021-10-26 /pmc/articles/PMC8576183/ /pubmed/34765596 http://dx.doi.org/10.3389/fbioe.2021.768927 Text en Copyright © 2021 Li, Zhang and Liu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Li, Wenling
Zhang, Guilong
Liu, Lu
Near-Infrared Inorganic Nanomaterials for Precise Diagnosis and Therapy
title Near-Infrared Inorganic Nanomaterials for Precise Diagnosis and Therapy
title_full Near-Infrared Inorganic Nanomaterials for Precise Diagnosis and Therapy
title_fullStr Near-Infrared Inorganic Nanomaterials for Precise Diagnosis and Therapy
title_full_unstemmed Near-Infrared Inorganic Nanomaterials for Precise Diagnosis and Therapy
title_short Near-Infrared Inorganic Nanomaterials for Precise Diagnosis and Therapy
title_sort near-infrared inorganic nanomaterials for precise diagnosis and therapy
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576183/
https://www.ncbi.nlm.nih.gov/pubmed/34765596
http://dx.doi.org/10.3389/fbioe.2021.768927
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