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Involvement of the TGF-β Signaling Pathway in the Development of YAP-Driven Osteosarcoma Lung Metastasis
BACKGROUND: The poor survival rate of patients with osteosarcoma (OS), specifically with metastases at diagnosis, undergoes the urgency to develop new therapeutic strategies. Although we recently demonstrated the key role of YAP/TEAD signaling in the growth of OS primary tumor, the molecular mechani...
Autores principales: | Morice, Sarah, Danieau, Geoffroy, Tesfaye, Robel, Mullard, Mathilde, Brion, Régis, Dupuy, Maryne, Ory, Benjamin, Brounais-Le Royer, Bénédicte, Corre, Isabelle, Redini, Françoise, Verrecchia, Franck |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576330/ https://www.ncbi.nlm.nih.gov/pubmed/34765560 http://dx.doi.org/10.3389/fonc.2021.765711 |
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