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S100A9 Activates the Immunosuppressive Switch Through the PI3K/Akt Pathway to Maintain the Immune Suppression Function of Testicular Macrophages

Macrophages are functionally plastic and can thus play different roles in various microenvironments. Testis is an immune privileged organ, and testicular macrophages (TMs) show special immunosuppressive phenotype and low response to various inflammatory stimuli. However, the underlying mechanism to...

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Detalles Bibliográficos
Autores principales: Fan, Zun Pan, Peng, Mei Lin, Chen, Yuan Yao, Xia, Yu Ze, Liu, Chun Yan, Zhao, Kai, Zhang, Hui Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576360/
https://www.ncbi.nlm.nih.gov/pubmed/34764959
http://dx.doi.org/10.3389/fimmu.2021.743354