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A Study on the Fabrication of an Effective Natural Substance Based on Schisandra chinensis Extracted Fermentation

PURPOSE: In this study, a high-efficiency Schisandra chinensis extract (SCE) produced by the fermentation of effective microorganisms (EM) was used as an antioxidant material in preparing cosmetic products. SUBJECTS AND METHODS: We conducted the study by extracting S. chinensis via EM fermentation t...

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Autores principales: Nguyen, Chi Thanh, Han, Jong-Man, Tran, Van Huong, Jeong, Hun, Kim, Eun Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576409/
https://www.ncbi.nlm.nih.gov/pubmed/34764664
http://dx.doi.org/10.2147/CCID.S336280
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author Nguyen, Chi Thanh
Han, Jong-Man
Tran, Van Huong
Jeong, Hun
Kim, Eun Sook
author_facet Nguyen, Chi Thanh
Han, Jong-Man
Tran, Van Huong
Jeong, Hun
Kim, Eun Sook
author_sort Nguyen, Chi Thanh
collection PubMed
description PURPOSE: In this study, a high-efficiency Schisandra chinensis extract (SCE) produced by the fermentation of effective microorganisms (EM) was used as an antioxidant material in preparing cosmetic products. SUBJECTS AND METHODS: We conducted the study by extracting S. chinensis via EM fermentation to increase the efficiency. Tyrosinase inhibitory factor analysis, pH, and thermal stability were measured to verify the properties of the prepared products. RESULTS: The efficacy and whitening effects of the prepared substances were verified using tyrosinase inhibitory factor analysis. As a result, it was found that both the SCE and SCE fermentation (SCEF) exhibited high, naturally originating, antioxidation ability. In addition, the pH and thermal stability of the substances were evaluated to optimize the cosmetic fabrication conditions. In this context, as the concentration of the added extract increased, the pH value decreased. The evaluation of safety and stability indicated that the substances contained effective chemical components having antioxidant activity, suppressing skin aging, and whitening effects in a weak acid range consistent with a pH of 6.25–2.98. Furthermore, there were no safety problems with the use of the obtained products even after they had been stored for 60 days. CONCLUSION: The SCE substance is demonstrated as a possible material for cosmetic application.
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spelling pubmed-85764092021-11-10 A Study on the Fabrication of an Effective Natural Substance Based on Schisandra chinensis Extracted Fermentation Nguyen, Chi Thanh Han, Jong-Man Tran, Van Huong Jeong, Hun Kim, Eun Sook Clin Cosmet Investig Dermatol Original Research PURPOSE: In this study, a high-efficiency Schisandra chinensis extract (SCE) produced by the fermentation of effective microorganisms (EM) was used as an antioxidant material in preparing cosmetic products. SUBJECTS AND METHODS: We conducted the study by extracting S. chinensis via EM fermentation to increase the efficiency. Tyrosinase inhibitory factor analysis, pH, and thermal stability were measured to verify the properties of the prepared products. RESULTS: The efficacy and whitening effects of the prepared substances were verified using tyrosinase inhibitory factor analysis. As a result, it was found that both the SCE and SCE fermentation (SCEF) exhibited high, naturally originating, antioxidation ability. In addition, the pH and thermal stability of the substances were evaluated to optimize the cosmetic fabrication conditions. In this context, as the concentration of the added extract increased, the pH value decreased. The evaluation of safety and stability indicated that the substances contained effective chemical components having antioxidant activity, suppressing skin aging, and whitening effects in a weak acid range consistent with a pH of 6.25–2.98. Furthermore, there were no safety problems with the use of the obtained products even after they had been stored for 60 days. CONCLUSION: The SCE substance is demonstrated as a possible material for cosmetic application. Dove 2021-11-02 /pmc/articles/PMC8576409/ /pubmed/34764664 http://dx.doi.org/10.2147/CCID.S336280 Text en © 2021 Nguyen et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Nguyen, Chi Thanh
Han, Jong-Man
Tran, Van Huong
Jeong, Hun
Kim, Eun Sook
A Study on the Fabrication of an Effective Natural Substance Based on Schisandra chinensis Extracted Fermentation
title A Study on the Fabrication of an Effective Natural Substance Based on Schisandra chinensis Extracted Fermentation
title_full A Study on the Fabrication of an Effective Natural Substance Based on Schisandra chinensis Extracted Fermentation
title_fullStr A Study on the Fabrication of an Effective Natural Substance Based on Schisandra chinensis Extracted Fermentation
title_full_unstemmed A Study on the Fabrication of an Effective Natural Substance Based on Schisandra chinensis Extracted Fermentation
title_short A Study on the Fabrication of an Effective Natural Substance Based on Schisandra chinensis Extracted Fermentation
title_sort study on the fabrication of an effective natural substance based on schisandra chinensis extracted fermentation
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576409/
https://www.ncbi.nlm.nih.gov/pubmed/34764664
http://dx.doi.org/10.2147/CCID.S336280
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