Magnolol Attenuates Right Ventricular Hypertrophy and Fibrosis in Hypoxia-Induced Pulmonary Arterial Hypertensive Rats Through Inhibition of the JAK2/STAT3 Signaling Pathway

Right ventricular (RV) remodeling is one of the essential pathological features in pulmonary arterial hypertension (PAH). RV hypertrophy or fibrosis are the leading causes of RV remodeling. Magnolol (6, 6′, 7, 12-tetramethoxy-2,2′-dimethyl-1-β-berbaman, C18H18O2) is a compound isolated from Magnolia...

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Detalles Bibliográficos
Autores principales: Fu, Minyi, Luo, Fangmei, Wang, Eli, Jiang, Yueping, Liu, Shao, Peng, Jun, Liu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576411/
https://www.ncbi.nlm.nih.gov/pubmed/34764873
http://dx.doi.org/10.3389/fphar.2021.755077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576411/
https://www.ncbi.nlm.nih.gov/pubmed/34764873
http://dx.doi.org/10.3389/fphar.2021.755077

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