TM4SF5 Knockout Protects Mice From Diet-Induced Obesity Partly by Regulating Autophagy in Adipose Tissue

Transmembrane 4 L six family member 5 (TM4SF5) functions as a sensor for lysosomal arginine levels and activates the mammalian target of rapamycin complex 1 (mTORC1). While the mTORC1 signaling pathway plays a key role in adipose tissue metabolism, the regulatory function of TM4SF5 in adipocytes rem...

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Detalles Bibliográficos
Autores principales: Choi, Cheoljun, Son, Yeonho, Kim, Jinyoung, Cho, Yoon Keun, Saha, Abhirup, Kim, Minsu, Im, Hyeonyeong, Kim, Kyungmin, Han, Juhyeong, Lee, Jung Weon, Seong, Je Kyung, Lee, Yun-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2021
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576418/
https://www.ncbi.nlm.nih.gov/pubmed/34187836
http://dx.doi.org/10.2337/db21-0145

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