Cargando…
Icaritin-Induced FAM99A Affects GLUT1-Mediated Glycolysis via Regulating the JAK2/STAT3 Pathway in Hepatocellular Carcinoma
Icaritin is a potential treatment option for hepatocellular carcinoma (HCC) based on the results of its phase 2 stage trial. Glucose transporter 1 (GLUT1), a critical gene in regulating glycolysis, has been recognized as a promising target in HCC treatment. Previous studies have reported that FAM99A...
Autores principales: | Zheng, Xia, Gou, Yudong, Jiang, Ziyu, Yang, Aizhen, Yang, Zhihui, Qin, Shukui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576446/ https://www.ncbi.nlm.nih.gov/pubmed/34765550 http://dx.doi.org/10.3389/fonc.2021.740557 |
Ejemplares similares
-
Icaritin Inhibits JAK/STAT3 Signaling and Growth of Renal Cell Carcinoma
por: Li, Shasha, et al.
Publicado: (2013) -
Icaritin suppresses multiple myeloma, by inhibiting IL-6/JAK2/STAT3
por: Zhu, Shicong, et al.
Publicado: (2015) -
A novel anti-cancer agent Icaritin suppresses hepatocellular carcinoma initiation and malignant growth through the IL-6/Jak2/Stat3 pathway
por: Zhao, Hong, et al.
Publicado: (2015) -
Mechanism of action of icaritin on uterine corpus endometrial carcinoma based on network pharmacology and experimental evaluation
por: Jin, Yan-Bin, et al.
Publicado: (2023) -
Nanomedicine‐boosting icaritin-based immunotherapy of advanced hepatocellular carcinoma
por: Lu, Yi, et al.
Publicado: (2022)