Isolation and Characterization of Mouse Monoclonal Antibodies That Neutralize SARS-CoV-2 and Its Variants of Concern Alpha, Beta, Gamma and Delta by Binding Conformational Epitopes of Glycosylated RBD With High Potency

Antibodies targeting Receptor Binding Domain (RBD) of SARS-CoV-2 have been suggested to account for the majority of neutralizing activity in COVID-19 convalescent sera and several neutralizing antibodies (nAbs) have been isolated, characterized and proposed as emergency therapeutics in the form of m...

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Detalles Bibliográficos
Autores principales: Mariotti, Sabrina, Capocefalo, Antonio, Chiantore, Maria Vincenza, Iacobino, Angelo, Teloni, Raffaela, De Angelis, Maria Laura, Gallinaro, Alessandra, Pirillo, Maria Franca, Borghi, Martina, Canitano, Andrea, Michelini, Zuleika, Baggieri, Melissa, Marchi, Antonella, Bucci, Paola, McKay, Paul F., Acchioni, Chiara, Sandini, Silvia, Sgarbanti, Marco, Tosini, Fabio, Di Virgilio, Antonio, Venturi, Giulietta, Marino, Francesco, Esposito, Valeria, Di Bonito, Paola, Magurano, Fabio, Cara, Andrea, Negri, Donatella, Nisini, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576447/
https://www.ncbi.nlm.nih.gov/pubmed/34764961
http://dx.doi.org/10.3389/fimmu.2021.750386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576447/
https://www.ncbi.nlm.nih.gov/pubmed/34764961
http://dx.doi.org/10.3389/fimmu.2021.750386

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