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Isolation and Characterization of Mouse Monoclonal Antibodies That Neutralize SARS-CoV-2 and Its Variants of Concern Alpha, Beta, Gamma and Delta by Binding Conformational Epitopes of Glycosylated RBD With High Potency
Antibodies targeting Receptor Binding Domain (RBD) of SARS-CoV-2 have been suggested to account for the majority of neutralizing activity in COVID-19 convalescent sera and several neutralizing antibodies (nAbs) have been isolated, characterized and proposed as emergency therapeutics in the form of m...
Autores principales: | Mariotti, Sabrina, Capocefalo, Antonio, Chiantore, Maria Vincenza, Iacobino, Angelo, Teloni, Raffaela, De Angelis, Maria Laura, Gallinaro, Alessandra, Pirillo, Maria Franca, Borghi, Martina, Canitano, Andrea, Michelini, Zuleika, Baggieri, Melissa, Marchi, Antonella, Bucci, Paola, McKay, Paul F., Acchioni, Chiara, Sandini, Silvia, Sgarbanti, Marco, Tosini, Fabio, Di Virgilio, Antonio, Venturi, Giulietta, Marino, Francesco, Esposito, Valeria, Di Bonito, Paola, Magurano, Fabio, Cara, Andrea, Negri, Donatella, Nisini, Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576447/ https://www.ncbi.nlm.nih.gov/pubmed/34764961 http://dx.doi.org/10.3389/fimmu.2021.750386 |
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