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Targeting Epigenetic Modifiers Can Reduce the Clonogenic Capacities of Sézary Cells

Sézary syndrome (SS) is an aggressive leukemic variant of cutaneous T-cell lymphomas (CTCL) in which the human Telomerase Reverse Transcriptase (hTERT) gene is re-expressed. Current available treatments do not provide long-term response. We previously reported that Histone deacetylase inhibitors (HD...

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Detalles Bibliográficos
Autores principales: Chebly, Alain, Prochazkova-Carlotti, Martina, Idrissi, Yamina, Bresson-Bepoldin, Laurence, Poglio, Sandrine, Farra, Chantal, Beylot-Barry, Marie, Merlio, Jean-Philippe, Tomb, Roland, Chevret, Edith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576518/
https://www.ncbi.nlm.nih.gov/pubmed/34765562
http://dx.doi.org/10.3389/fonc.2021.775253