Cargando…

Ocular Wnt/β-Catenin Pathway Inhibitor XAV939-Loaded Liposomes for Treating Alkali-Burned Corneal Wound and Neovascularization

Corneal wound involves a series of complex and coordinated physiological processes, leading to persistent epithelial defects and opacification. An obstacle in the treatment of ocular diseases is poor drug delivery and maintenance. In this study, we constructed a Wnt/β-catenin pathway inhibitor, XAV9...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhong, Yueyang, Wang, Kai, Zhang, Yin, Yin, Qichuan, Li, Su, Wang, Jiaming, Zhang, Xiaobo, Han, Haijie, Yao, Ke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576519/ https://www.ncbi.nlm.nih.gov/pubmed/34765592 http://dx.doi.org/10.3389/fbioe.2021.753879

Ejemplares similares

Ferrostatin‐1‐loaded liposome for treatment of corneal alkali burn via targeting ferroptosis
por: Wang, Kai, et al.
Publicado: (2021)

Bioactivity Studies of Hesperidin and XAV939
por: Fazary, Ahmed E., et al.
Publicado: (2021)

Targeting Wnt/β-catenin signaling using XAV939 nanoparticles in tumor microenvironment-conditioned macrophages promote immunogenicity
por: Pundkar, Chetan, et al.
Publicado: (2023)

Docetaxel Resistance in Castration-Resistant Prostate Cancer: Transcriptomic Determinants and the Effect of Inhibiting Wnt/β-Catenin Signaling by XAV939
por: Pudova, Elena, et al.
Publicado: (2022)

XAV939 inhibits the proliferation and migration of lung adenocarcinoma A549 cells through the WNT pathway
por: Li, Chong, et al.
Publicado: (2018)

XAV939, a tankyrase 1 inhibitior, promotes cell apoptosis in neuroblastoma cell lines by inhibiting Wnt/β-catenin signaling pathway
por: Tian, Xiao-Hong, et al.
Publicado: (2013)

XAV939-Mediated ARTD Activity Inhibition in Human MB Cell Lines
por: Renna, Cristiano, et al.
Publicado: (2015)

Treatment with XAV-939 prevents in vitro calcification of human valvular interstitial cells
por: Dittfeld, Claudia, et al.
Publicado: (2018)

Minocycline Inhibits Alkali Burn-Induced Corneal Neovascularization in Mice
por: Xiao, Ou, et al.
Publicado: (2012)

Low Dose of Paclitaxel Combined with XAV939 Attenuates Metastasis, Angiogenesis and Growth in Breast Cancer by Suppressing Wnt Signaling
por: Shetti, Dattatrya, et al.
Publicado: (2019)

Comparison of genome-wide gene expression in suture- and alkali burn-induced murine corneal neovascularization
por: Jia, Changkai, et al.
Publicado: (2011)

The WNT/β-catenin signaling inhibitor XAV939 enhances the elimination of LNCaP and PC-3 prostate cancer cells by prostate cancer patient lymphocytes in vitro
por: Stakheev, Dmitry, et al.
Publicado: (2019)

Tankyrase 1 inhibitior XAV939 increases chemosensitivity in colon cancer cell lines via inhibition of the Wnt signaling pathway
por: WU, XUEFANG, et al.
Publicado: (2016)

Wnt inhibitor XAV939 suppresses the viability of small cell lung cancer NCI-H446 cells and induces apoptosis
por: Guo, Wenxuan, et al.
Publicado: (2017)

Inhibition of Neovascularization and Inflammation in a Mouse Model of Corneal Alkali Burns Using Cationic Liposomal Tacrolimus
por: Lin, Xueqi, et al.
Publicado: (2021)

Tankyrase inhibitor XAV-939 enhances osteoblastogenesis and mineralization of human skeletal (mesenchymal) stem cells
por: Almasoud, Nuha, et al.
Publicado: (2020)

MicroRNA-296 mediated corneal neovascularization in an animal model of corneal burns after alkali exposures
por: Ji, Kai-Bao, et al.
Publicado: (2018)

Modelling of a targeted nanotherapeutic ‘stroma’ to deliver the cytokine LIF, or XAV939, a potent inhibitor of Wnt–β-catenin signalling, for use in human fetal dopaminergic grafts in Parkinson’s disease
por: Zhao, Jing-Wei, et al.
Publicado: (2014)

Author Correction: Tankyrase inhibitor XAV-939 enhances osteoblastogenesis and mineralization of human skeletal (mesenchymal) stem cells
por: Almasoud, Nuha, et al.
Publicado: (2021)

Effect of Collagen Cross-Linking on Alkali Burn-Induced Corneal Neovascularization in Rabbits
por: Xu, Xiaoying, et al.
Publicado: (2018)

Rhamnazin attenuates inflammation and inhibits alkali burn-induced corneal neovascularization in rats
por: Yu, Yao, et al.
Publicado: (2018)

Therapeutic Effects of Topical Netrin-4 Inhibits Corneal Neovascularization in Alkali-Burn Rats
por: Han, Yun, et al.
Publicado: (2015)

Anticancer effect of XAV939 is observed by inhibiting lactose dehydrogenase A in a 3-dimensional culture of colorectal cancer cells
por: Kim, Dahee, et al.
Publicado: (2019)

In Vitro Differentiation of Neural-Like Cells from Human Embryonic Stem Cells by A Combination of Dorsomorphin, XAV939, and A8301
por: Valizadeh-Arshad, Zahra, et al.
Publicado: (2018)

Inhibited corneal neovascularization in rabbits following corneal alkali burn by double-target interference for VEGF and HIF-1α
por: Fu, Ying-Cong, et al.
Publicado: (2019)

Quantitative Proteomic Analysis of 2D and 3D Cultured Colorectal Cancer Cells: Profiling of Tankyrase Inhibitor XAV939-Induced Proteome
por: Kim, Young Eun, et al.
Publicado: (2018)

Inhibition of mouse alkali burn induced-corneal neovascularization by recombinant adenovirus encoding human vasohibin-1
por: Zhou, Shi-you, et al.
Publicado: (2010)

Fasudil hydrochloride, a potent ROCK inhibitor, inhibits corneal neovascularization after alkali burns in mice
por: Zeng, Peng, et al.
Publicado: (2015)

The inhibitory effect of different concentrations of KH902 eye drops on corneal neovascularization induced by alkali burn
por: Wu, Yan, et al.
Publicado: (2017)

Subconjunctival injection of antagomir-21 alleviates corneal neovascularization in a mouse model of alkali-burned cornea
por: Zhang, Yun, et al.
Publicado: (2016)

Forkhead Domain Inhibitor-6 Suppresses Corneal Neovascularization and Subsequent Fibrosis After Alkali Burn in Rats
por: Lan, Chunlin, et al.
Publicado: (2022)

Inhibitory effects of (90)Sr/(90)Y β-irradiation on alkali burn-induced corneal neovascularization in rats
por: LIN, YUANQIANG, et al.
Publicado: (2016)

Inhibitory effects of S100A4 gene silencing on alkali burn-induced corneal neovascularization: an in vivo study
por: Wang, Yu-Lin, et al.
Publicado: (2017)

Topical Pirfenidone-Loaded Liposomes Ophthalmic Formulation Reduces Haze Development after Corneal Alkali Burn in Mice
por: Diaz-Palomera, Carlos Daniel, et al.
Publicado: (2022)

Liposome–trimethyl chitosan nanoparticles codeliver insulin and siVEGF to treat corneal alkali burns by inhibiting ferroptosis
por: Xiong, Xiaojing, et al.
Publicado: (2023)

Erratum: Inhibitory effects of S100A4 gene silencing on alkali burn-induced corneal neovascularization: an in vivo study
Publicado: (2020)

RNA sequencing uncovers the key long non-coding RNAs and potential molecular mechanism contributing to XAV939-mediated inhibition of non-small cell lung cancer
por: Yu, Haixiang, et al.
Publicado: (2019)

The long-term effect of tacrolimus on alkali burn-induced corneal neovascularization and inflammation surpasses that of anti-vascular endothelial growth factor
por: Chen, Ling, et al.
Publicado: (2018)

Inhibition of PDGF-BB reduces alkali-induced corneal neovascularization in mice
por: Chen, Lei, et al.
Publicado: (2021)

Involvement of NADPH oxidases in alkali burn-induced corneal injury
por: GU, XUE-JUN, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_8833r02mc6famionv8ild0l3bm