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A DOT1B/Ribonuclease H2 Protein Complex Is Involved in R-Loop Processing, Genomic Integrity, and Antigenic Variation in Trypanosoma brucei

The parasite Trypanosoma brucei periodically changes the expression of protective variant surface glycoproteins (VSGs) to evade its host’s immune system in a process known as antigenic variation. One route to change VSG expression is the transcriptional activation of a previously silent VSG expressi...

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Detalles Bibliográficos
Autores principales:	Eisenhuth, Nicole, Vellmer, Tim, Rauh, Elisa T., Butter, Falk, Janzen, Christian J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576533/ https://www.ncbi.nlm.nih.gov/pubmed/34749530 http://dx.doi.org/10.1128/mBio.01352-21

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