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Oncogenic Integration of Nucleotide Metabolism via Fatty Acid Synthase in Non-Hodgkin Lymphoma
Metabolic dysfunctions enabling increased nucleotide biosynthesis are necessary for supporting malignant proliferation. Our investigations indicate that upregulation of fatty acid synthase (FASN) and de novo lipogenesis, commonly observed in many cancers, are associated with nucleotide metabolic dys...
Autores principales: | Ravi, Dashnamoorthy, Beheshti, Afshin, Abermil, Nasséra, Lansigan, Frederick, Kinlaw, William, Matthan, Nirupa R., Mokhtar, Maisarah, Passero, Frank C., Puliti, Patrick, David, Kevin A., Dolnikowski, Gregory G., Su, Xiaoyang, Chen, Ying, Bijan, Mahboubi, Varshney, Rohan R., Kim, Baek, Dave, Sandeep S., Rudolph, Michael C., Evens, Andrew M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576537/ https://www.ncbi.nlm.nih.gov/pubmed/34765544 http://dx.doi.org/10.3389/fonc.2021.725137 |
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