Shikonin regulates autophagy via the AMPK/mTOR pathway and reduces apoptosis of human umbilical cord mesenchymal stem cells to improve survival in tissues surrounding brain contusion

Shikonin has been reported to regulate autophagy via the AMP-activated protein kinase (AMPK)/mTOR signalling pathway and decrease apoptosis in transplanted human umbilical cord mesenchymal stem cells (HUMSCs). In the present study, HUMSCs were exposed to oxygen glucose deprivation (OGD) in vitro for...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaohong, Huang, Lijie, Wu, Ke, Sun, Zhezhe, Wang, Kankai, Ru, Junnan, Zhuge, Qichuan, Ruan, Linhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576632/
https://www.ncbi.nlm.nih.gov/pubmed/34765016
http://dx.doi.org/10.3892/etm.2021.10910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576632/
https://www.ncbi.nlm.nih.gov/pubmed/34765016
http://dx.doi.org/10.3892/etm.2021.10910

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