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Berberine attenuates atherosclerotic lesions and hepatic steatosis in ApoE(-/-) mice by down-regulating PCSK9 via ERK1/2 pathway

BACKGROUND: It has been demonstrated that berberine (BBR), a kind of alkaloid derived from Chinese herbal medicine, has multiple pharmacological effects on human’s diseases including anti-atherosclerosis action. However, although the previous studies showed that the beneficial impact of BBR on ather...

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Detalles Bibliográficos
Autores principales: Ma, Chun-Yan, Shi, Xiao-Yun, Wu, Ya-Ru, Zhang, Yue, Yao, Yu-Hong, Qu, Hui-Lin, Zhang, Wei, Guo, Yuan-Lin, Xu, Rui-Xia, Li, Jian-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576642/
https://www.ncbi.nlm.nih.gov/pubmed/34790723
http://dx.doi.org/10.21037/atm-20-8106