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MYO1B enhances colorectal cancer metastasis by promoting the F-actin rearrangement and focal adhesion assembly via RhoA/ROCK/FAK signaling

BACKGROUND: Colorectal cancer (CRC) has a high worldwide incidence and mortality. Tumor metastasis is one of the primary reasons for the poor prognosis of CRC patients. However, the mechanism underlying CRC metastasis is still unclear. Myosin 1B (MYO1B) is important for cell migration and motility a...

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Detalles Bibliográficos
Autores principales: Xie, Lang, Huang, Hongyun, Zheng, Zheng, Yang, Qian, Wang, Shubo, Chen, Yaoxu, Yu, Jinlong, Cui, Chunhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576704/
https://www.ncbi.nlm.nih.gov/pubmed/34790749
http://dx.doi.org/10.21037/atm-21-4702