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WDR60-mediated dynein-2 loading into cilia powers retrograde IFT and transition zone crossing

The dynein-2 motor complex drives retrograde intraflagellar transport (IFT), playing a pivotal role in the assembly and functions of cilia. However, the mechanisms that regulate dynein-2 motility remain poorly understood. Here, we identify the Caenorhabditis elegans WDR60 homologue, WDR-60, and diss...

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Detalles Bibliográficos
Autores principales:	De-Castro, Ana R.G., Rodrigues, Diogo R.M., De-Castro, Maria J.G., Vieira, Neide, Vieira, Cármen, Carvalho, Ana X., Gassmann, Reto, Abreu, Carla M.C., Dantas, Tiago J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576871/ https://www.ncbi.nlm.nih.gov/pubmed/34739033 http://dx.doi.org/10.1083/jcb.202010178

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