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Icariin improves testicular dysfunction via enhancing proliferation and inhibiting mitochondria-dependent apoptosis pathway in high-fat diet and streptozotocin-induced diabetic rats

BACKGROUND: Diabetes mellitus (DM), a chronic metabolic disease, severely impairs male reproductive function. However, the underpinning mechanisms are still incompletely defined, and there are no effective strategies or medicines for these reproductive lesions. Icariin (ICA), the main active compone...

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Detalles Bibliográficos
Autores principales: He, Weiguo, Liu, Huiqing, Hu, Linlin, Wang, Yaohui, Huang, Lane, Liang, Aihong, Wang, Xuan, Zhang, Qing, Chen, Yi, Cao, Yi, Li, Suyun, Wang, Junli, Lei, Xiaocan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576896/
https://www.ncbi.nlm.nih.gov/pubmed/34753504
http://dx.doi.org/10.1186/s12958-021-00851-9