Therapeutic inhibition of GAS6-AS1/YBX1/MYC axis suppresses cell propagation and disease progression of acute myeloid leukemia

BACKGROUND: Acute myeloid leukemia (AML) is the most common type of leukemia in adults. Its therapy has not significantly improved during the past four decades despite intense research efforts. New molecularly targeted therapies are in great need. The proto-oncogene c-Myc (MYC) is an attractive targ...

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Detalles Bibliográficos
Autores principales: Zhou, Hao, Liu, Wei, Zhou, Yongming, Hong, Zhenya, Ni, Jian, Zhang, Xiaoping, Li, Ziping, Li, Mengyuan, He, Wenjuan, Zhang, Donghua, Chen, Xuexing, Zhu, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576903/
https://www.ncbi.nlm.nih.gov/pubmed/34753494
http://dx.doi.org/10.1186/s13046-021-02145-9

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