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Application of artificial intelligence ensemble learning model in early prediction of atrial fibrillation
BACKGROUND: Atrial fibrillation is a paroxysmal heart disease without any obvious symptoms for most people during the onset. The electrocardiogram (ECG) at the time other than the onset of this disease is not significantly different from that of normal people, which makes it difficult to detect and...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576960/ https://www.ncbi.nlm.nih.gov/pubmed/34749631 http://dx.doi.org/10.1186/s12859-021-04000-2 |
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author | Wu, Cai Hwang, Maxwell Huang, Tian-Hsiang Chen, Yen-Ming J. Chang, Yiu-Jen Ho, Tsung-Han Huang, Jian Hwang, Kao-Shing Ho, Wen-Hsien |
author_facet | Wu, Cai Hwang, Maxwell Huang, Tian-Hsiang Chen, Yen-Ming J. Chang, Yiu-Jen Ho, Tsung-Han Huang, Jian Hwang, Kao-Shing Ho, Wen-Hsien |
author_sort | Wu, Cai |
collection | PubMed |
description | BACKGROUND: Atrial fibrillation is a paroxysmal heart disease without any obvious symptoms for most people during the onset. The electrocardiogram (ECG) at the time other than the onset of this disease is not significantly different from that of normal people, which makes it difficult to detect and diagnose. However, if atrial fibrillation is not detected and treated early, it tends to worsen the condition and increase the possibility of stroke. In this paper, P-wave morphology parameters and heart rate variability feature parameters were simultaneously extracted from the ECG. A total of 31 parameters were used as input variables to perform the modeling of artificial intelligence ensemble learning model. RESULTS: This paper applied three artificial intelligence ensemble learning methods, namely Bagging ensemble learning method, AdaBoost ensemble learning method, and Stacking ensemble learning method. The prediction results of these three artificial intelligence ensemble learning methods were compared. As a result of the comparison, the Stacking ensemble learning method combined with various models finally obtained the best prediction effect with the accuracy of 92%, sensitivity of 88%, specificity of 96%, positive predictive value of 95.7%, negative predictive value of 88.9%, F1 score of 0.9231 and area under receiver operating characteristic curve value of 0.911. CONCLUSION: In feature extraction, this paper combined P-wave morphology parameters and heart rate variability parameters as input parameters for model training, and validated the value of the proposed parameters combination for the improvement of the model’s predicting effect. In the calculation of the P-wave morphology parameters, the hybrid Taguchi-genetic algorithm was used to obtain more accurate Gaussian function fitting parameters. The prediction model was trained using the Stacking ensemble learning method, so that the model accuracy had better results, which can further improve the early prediction of atrial fibrillation. |
format | Online Article Text |
id | pubmed-8576960 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-85769602021-11-10 Application of artificial intelligence ensemble learning model in early prediction of atrial fibrillation Wu, Cai Hwang, Maxwell Huang, Tian-Hsiang Chen, Yen-Ming J. Chang, Yiu-Jen Ho, Tsung-Han Huang, Jian Hwang, Kao-Shing Ho, Wen-Hsien BMC Bioinformatics Research BACKGROUND: Atrial fibrillation is a paroxysmal heart disease without any obvious symptoms for most people during the onset. The electrocardiogram (ECG) at the time other than the onset of this disease is not significantly different from that of normal people, which makes it difficult to detect and diagnose. However, if atrial fibrillation is not detected and treated early, it tends to worsen the condition and increase the possibility of stroke. In this paper, P-wave morphology parameters and heart rate variability feature parameters were simultaneously extracted from the ECG. A total of 31 parameters were used as input variables to perform the modeling of artificial intelligence ensemble learning model. RESULTS: This paper applied three artificial intelligence ensemble learning methods, namely Bagging ensemble learning method, AdaBoost ensemble learning method, and Stacking ensemble learning method. The prediction results of these three artificial intelligence ensemble learning methods were compared. As a result of the comparison, the Stacking ensemble learning method combined with various models finally obtained the best prediction effect with the accuracy of 92%, sensitivity of 88%, specificity of 96%, positive predictive value of 95.7%, negative predictive value of 88.9%, F1 score of 0.9231 and area under receiver operating characteristic curve value of 0.911. CONCLUSION: In feature extraction, this paper combined P-wave morphology parameters and heart rate variability parameters as input parameters for model training, and validated the value of the proposed parameters combination for the improvement of the model’s predicting effect. In the calculation of the P-wave morphology parameters, the hybrid Taguchi-genetic algorithm was used to obtain more accurate Gaussian function fitting parameters. The prediction model was trained using the Stacking ensemble learning method, so that the model accuracy had better results, which can further improve the early prediction of atrial fibrillation. BioMed Central 2021-11-08 /pmc/articles/PMC8576960/ /pubmed/34749631 http://dx.doi.org/10.1186/s12859-021-04000-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Wu, Cai Hwang, Maxwell Huang, Tian-Hsiang Chen, Yen-Ming J. Chang, Yiu-Jen Ho, Tsung-Han Huang, Jian Hwang, Kao-Shing Ho, Wen-Hsien Application of artificial intelligence ensemble learning model in early prediction of atrial fibrillation |
title | Application of artificial intelligence ensemble learning model in early prediction of atrial fibrillation |
title_full | Application of artificial intelligence ensemble learning model in early prediction of atrial fibrillation |
title_fullStr | Application of artificial intelligence ensemble learning model in early prediction of atrial fibrillation |
title_full_unstemmed | Application of artificial intelligence ensemble learning model in early prediction of atrial fibrillation |
title_short | Application of artificial intelligence ensemble learning model in early prediction of atrial fibrillation |
title_sort | application of artificial intelligence ensemble learning model in early prediction of atrial fibrillation |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576960/ https://www.ncbi.nlm.nih.gov/pubmed/34749631 http://dx.doi.org/10.1186/s12859-021-04000-2 |
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