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A case report of testicular diffuse large B-cell malignant lymphoma with cutaneous metastasis: A rare entity

INTRODUCTION AND IMPORTANCE: Primary testicular lymphoma (PTL) is a variety of extra-nodal lymphoma taking origin from testis. It accounts 5% of all testicular tumors. Metastasis may occur in contralateral testis, bone, central nervous system and rarely in skin. Herein, we present the case of testic...

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Autores principales: Hermi, Amine, Bibi, Mokhtar, Rahoui, Moez, Chelly, Beya, Rhouma, Sami Ben, Nouira, Yassine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577119/
https://www.ncbi.nlm.nih.gov/pubmed/34741852
http://dx.doi.org/10.1016/j.ijscr.2021.106519
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author Hermi, Amine
Bibi, Mokhtar
Rahoui, Moez
Chelly, Beya
Rhouma, Sami Ben
Nouira, Yassine
author_facet Hermi, Amine
Bibi, Mokhtar
Rahoui, Moez
Chelly, Beya
Rhouma, Sami Ben
Nouira, Yassine
author_sort Hermi, Amine
collection PubMed
description INTRODUCTION AND IMPORTANCE: Primary testicular lymphoma (PTL) is a variety of extra-nodal lymphoma taking origin from testis. It accounts 5% of all testicular tumors. Metastasis may occur in contralateral testis, bone, central nervous system and rarely in skin. Herein, we present the case of testicular diffuse large B-cell malignant lymphoma with cutaneous metastasis. CASE PRESENTATION: A 60-year-old male presented with swollen painless solid right testis, with homolateral inguinal nodes. Testicular tumors markers were within normal range. Right radical orchidectomy was performed. Histopathological examination concluded to the diagnosis of Diffuse Large B Cell Lymphoma. Four weeks later, the patient presented alteration of general condition and multiples cutaneous centimetric lesions located in the right inguinal region. Biopsy of this lesion confirmed the diagnosis of metastases from the testicular lymphoma. The patient deceased three days later, before starting further treatment. CLINICAL DISCUSSION: Primary testicular lymphoma is a rare variety of testicular tumors. The prognosis is poor. Metastasis may occur in different sites such as contralateral testis, central nervous system, and skin. The prognosis is usually poor in the rare case of cutaneous metastasis. CONCLUSION: Primary testicular tumor is an aggressive rare variety of testicular tumors with poor prognosis. Cutaneous metastasis is rarely reported. Cutaneous lesions should be explored and suspected to be malignant. Early treatment with rapid multidisciplinary management is the key for adequate approach.
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spelling pubmed-85771192021-11-12 A case report of testicular diffuse large B-cell malignant lymphoma with cutaneous metastasis: A rare entity Hermi, Amine Bibi, Mokhtar Rahoui, Moez Chelly, Beya Rhouma, Sami Ben Nouira, Yassine Int J Surg Case Rep Case Report INTRODUCTION AND IMPORTANCE: Primary testicular lymphoma (PTL) is a variety of extra-nodal lymphoma taking origin from testis. It accounts 5% of all testicular tumors. Metastasis may occur in contralateral testis, bone, central nervous system and rarely in skin. Herein, we present the case of testicular diffuse large B-cell malignant lymphoma with cutaneous metastasis. CASE PRESENTATION: A 60-year-old male presented with swollen painless solid right testis, with homolateral inguinal nodes. Testicular tumors markers were within normal range. Right radical orchidectomy was performed. Histopathological examination concluded to the diagnosis of Diffuse Large B Cell Lymphoma. Four weeks later, the patient presented alteration of general condition and multiples cutaneous centimetric lesions located in the right inguinal region. Biopsy of this lesion confirmed the diagnosis of metastases from the testicular lymphoma. The patient deceased three days later, before starting further treatment. CLINICAL DISCUSSION: Primary testicular lymphoma is a rare variety of testicular tumors. The prognosis is poor. Metastasis may occur in different sites such as contralateral testis, central nervous system, and skin. The prognosis is usually poor in the rare case of cutaneous metastasis. CONCLUSION: Primary testicular tumor is an aggressive rare variety of testicular tumors with poor prognosis. Cutaneous metastasis is rarely reported. Cutaneous lesions should be explored and suspected to be malignant. Early treatment with rapid multidisciplinary management is the key for adequate approach. Elsevier 2021-10-18 /pmc/articles/PMC8577119/ /pubmed/34741852 http://dx.doi.org/10.1016/j.ijscr.2021.106519 Text en © 2021 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Hermi, Amine
Bibi, Mokhtar
Rahoui, Moez
Chelly, Beya
Rhouma, Sami Ben
Nouira, Yassine
A case report of testicular diffuse large B-cell malignant lymphoma with cutaneous metastasis: A rare entity
title A case report of testicular diffuse large B-cell malignant lymphoma with cutaneous metastasis: A rare entity
title_full A case report of testicular diffuse large B-cell malignant lymphoma with cutaneous metastasis: A rare entity
title_fullStr A case report of testicular diffuse large B-cell malignant lymphoma with cutaneous metastasis: A rare entity
title_full_unstemmed A case report of testicular diffuse large B-cell malignant lymphoma with cutaneous metastasis: A rare entity
title_short A case report of testicular diffuse large B-cell malignant lymphoma with cutaneous metastasis: A rare entity
title_sort case report of testicular diffuse large b-cell malignant lymphoma with cutaneous metastasis: a rare entity
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577119/
https://www.ncbi.nlm.nih.gov/pubmed/34741852
http://dx.doi.org/10.1016/j.ijscr.2021.106519
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