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Endothelial GTPCH (GTP Cyclohydrolase 1) and Tetrahydrobiopterin Regulate Gestational Blood Pressure, Uteroplacental Remodeling, and Fetal Growth

Abnormal uteroplacental remodeling leads to placental hypoperfusion, causing fetal growth restriction and pregnancy-related hypertension, which are associated with endothelial dysfunction and markers of reduced vascular NO bioavailability and oxidative stress. Tetrahydrobiopterin (BH4) is a redox co...

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Detalles Bibliográficos
Autores principales:	Chuaiphichai, Surawee, Yu, Grace Z., Tan, Cheryl M.J., Whiteman, Christopher, Douglas, Gillian, Dickinson, Yasmin, Drydale, Edward N., Appari, Mahesh, Zhang, Wei, Crabtree, Mark J., McNeill, Eileen, Hale, Ashley B., Lewandowski, Adam J., Alp, Nicholas J., Vatish, Manu, Leeson, Paul, Channon, Keith M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577301/ https://www.ncbi.nlm.nih.gov/pubmed/34689592 http://dx.doi.org/10.1161/HYPERTENSIONAHA.120.17646

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