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Single Molecule Imaging of Transcription Dynamics in Somatic Stem Cells

Molecular noise is a natural phenomenon inherent to all biological systems(1,2). How stochastic processes give rise to the robust outcomes supportive of tissue homeostasis is a conundrum. Here, to quantitatively investigate this issue, we use single-molecule mRNA FISH (smFISH) on stem cells derived...

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Detalles Bibliográficos
Autores principales:	Wheat, Justin C., Sella, Yehonatan, Willcockson, Michael, Skoultchi, Arthur I., Bergman, Aviv, Singer, Robert H., Steidl, Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577313/ https://www.ncbi.nlm.nih.gov/pubmed/32581360 http://dx.doi.org/10.1038/s41586-020-2432-4

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