Probing Affinity, Avidity, Anticooperativity, and Competition in Antibody and Receptor Binding to the SARS-CoV-2 Spike by Single Particle Mass Analyses

[Image: see text] Determining how antibodies interact with the spike (S) protein of the SARS-CoV-2 virus is critical for combating COVID-19. Structural studies typically employ simplified, truncated constructs that may not fully recapitulate the behavior of the original complexes. Here, we combine t...

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Detalles Bibliográficos
Autores principales: Yin, Victor, Lai, Szu-Hsueh, Caniels, Tom G., Brouwer, Philip J. M., Brinkkemper, Mitch, Aldon, Yoann, Liu, Hejun, Yuan, Meng, Wilson, Ian A., Sanders, Rogier W., van Gils, Marit J., Heck, Albert J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577368/
https://www.ncbi.nlm.nih.gov/pubmed/34845440
http://dx.doi.org/10.1021/acscentsci.1c00804

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