Cooperation between CYB5R3 and NOX4 via coenzyme Q mitigates endothelial inflammation

NADPH oxidase 4 (NOX4) regulates endothelial inflammation by producing hydrogen peroxide (H(2)O(2)) and to a lesser extent O(2)(•-). The ratio of NOX4-derived H(2)O(2) and O(2)(•-) can be altered by coenzyme Q (CoQ) mimics. Therefore, we hypothesize that cytochrome b5 reductase 3 (CYB5R3), a CoQ red...

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Detalles Bibliográficos
Autores principales: Yuan, Shuai, Hahn, Scott A., Miller, Megan P., Sanker, Subramaniam, Calderon, Michael J., Sullivan, Mara, Dosunmu-Ogunbi, Atinuke M., Fazzari, Marco, Li, Yao, Reynolds, Michael, Wood, Katherine C., St Croix, Claudette M., Stolz, Donna, Cifuentes-Pagano, Eugenia, Navas, Placido, Shiva, Sruti, Schopfer, Francisco J., Pagano, Patrick J., Straub, Adam C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577475/
https://www.ncbi.nlm.nih.gov/pubmed/34656824
http://dx.doi.org/10.1016/j.redox.2021.102166

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