Novel role of xanthine oxidase-dependent H(2)O(2) production in 12/15-lipoxygenase-mediated de novo lipogenesis, triglyceride biosynthesis and weight gain

12/15-lipoxygenase (12/15-LOX) plays an essential role in oxidative conversion of polyunsaturated fatty acids into various bioactive lipid molecules. Although 12/15-LOX's role in the pathophysiology of various human diseases has been well studied, its role in weight gain is controversial and po...

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Detalles Bibliográficos
Autores principales: Govatati, Suresh, Pichavaram, Prahalathan, Mani, Arul M., Kumar, Raj, Sharma, Deepti, Dienel, Ari, Meena, Sunita, Puchowicz, Michelle A., Park, Edwards A., Rao, Gadiparthi N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577505/
https://www.ncbi.nlm.nih.gov/pubmed/34655995
http://dx.doi.org/10.1016/j.redox.2021.102163

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