Veliparib in Combination With Platinum-Based Chemotherapy for First-Line Treatment of Advanced Squamous Cell Lung Cancer: A Randomized, Multicenter Phase III Study

PURPOSE: Squamous non–small-cell lung cancer (sqNSCLC) is genetically complex with evidence of DNA damage. This phase III study investigated the efficacy and safety of poly (ADP-ribose) polymerase inhibitor veliparib in combination with conventional chemotherapy for advanced sqNSCLC (NCT02106546). P...

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Detalles Bibliográficos
Autores principales: Ramalingam, Suresh S., Novello, Silvia, Guclu, Salih Zeki, Bentsion, Dmitry, Zvirbule, Zanete, Szilasi, Maria, Bernabe, Reyes, Syrigos, Konstantinos, Byers, Lauren Averett, Clingan, Philip, Bar, Jair, Vokes, Everett E., Govindan, Ramaswamy, Dunbar, Martin, Ansell, Peter, He, Lei, Huang, Xin, Sehgal, Vasudha, Glasgow, Jaimee, Bach, Bruce A., Mazieres, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2021
Materias:
ORIGINAL REPORTS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577684/
https://www.ncbi.nlm.nih.gov/pubmed/34436928
http://dx.doi.org/10.1200/JCO.20.03318

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