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Shikonin suppresses colon cancer cell growth and exerts synergistic effects by regulating ADAM17 and the IL-6/STAT3 signaling pathway

Signal transducer and activator of transcription 3 (STAT3) activation is associated with drug resistance induced by anti-epidermal growth factor receptor (anti-EGFR) therapy in the treatment of colon cancer. Thus, the combined inhibition of EGFR and STAT3 may prove beneficial for this type of cancer...

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Detalles Bibliográficos
Autores principales:	Shi, Wei, Men, Lintong, Pi, Xiu, Jiang, Tao, Peng, Dewei, Huo, Shengqi, Luo, Pengcheng, Wang, Moran, Guo, Junyi, Jiang, Yue, Peng, Lulu, Lin, Li, Li, Sheng, Lv, Jiagao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577797/ https://www.ncbi.nlm.nih.gov/pubmed/34726248 http://dx.doi.org/10.3892/ijo.2021.5279

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