Parallel functional testing identifies enhancers active in early postnatal mouse brain

Enhancers are cis-regulatory elements that play critical regulatory roles in modulating developmental transcription programs and driving cell-type-specific and context-dependent gene expression in the brain. The development of massively parallel reporter assays (MPRAs) has enabled high-throughput fu...

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Detalles Bibliográficos
Autores principales: Lambert, Jason T, Su-Feher, Linda, Cichewicz, Karol, Warren, Tracy L, Zdilar, Iva, Wang, Yurong, Lim, Kenneth J, Haigh, Jessica L, Morse, Sarah J, Canales, Cesar P, Stradleigh, Tyler W, Castillo Palacios, Erika, Haghani, Viktoria, Moss, Spencer D, Parolini, Hannah, Quintero, Diana, Shrestha, Diwash, Vogt, Daniel, Byrne, Leah C, Nord, Alex S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577842/
https://www.ncbi.nlm.nih.gov/pubmed/34605404
http://dx.doi.org/10.7554/eLife.69479

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