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BMSC-Derived Exosomes Ameliorate Osteoarthritis by Inhibiting Pyroptosis of Cartilage via Delivering miR-326 Targeting HDAC3 and STAT1//NF-κB p65 to Chondrocytes
BACKGROUND: In the past decade, mesenchymal stem cells (MSCs) have been widely used for the treatment of osteoarthritis (OA), and noncoding RNAs in exosomes may play a major role. AIM: The present study is aimed at exploring the effect and mechanism of miR-326 in exosomes secreted by bone marrow mes...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577926/ https://www.ncbi.nlm.nih.gov/pubmed/34764819 http://dx.doi.org/10.1155/2021/9972805 |