Deubiquitinase USP5 promotes non-small cell lung cancer cell proliferation by stabilizing cyclin D1

BACKGROUND: Cyclin D1 (CCND1) is overexpressed in non-small cell lung cancer (NSCLC) and contributes to its tumorigenesis and progression. Accumulating evidence shows that ubiquitin-specific protease 5 (USP5), an important member of the USP family, acts as a tumor promoter by deubiquitinating and st...

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Detalles Bibliográficos
Autores principales: Zhang, Zhiwei, Cui, Zihan, Xie, Zhuolin, Li, Chang, Xu, Chun, Guo, Xia, Yu, Jie, Chen, Tengfei, Facchinetti, Francesco, Bohnenberger, Hanibal, Leong, Tracy L., Xie, Yufeng, Mao, Xinliang, Zhao, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577967/
https://www.ncbi.nlm.nih.gov/pubmed/34858787
http://dx.doi.org/10.21037/tlcr-21-767

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