A large-scale, multicentered trial evaluating the sensitivity and specificity of digital PCR versus ARMS-PCR for detecting ctDNA-based EGFR p.T790M in non-small-cell lung cancer patients

BACKGROUND: Developing liquid biopsy technology with higher sensitivity and specificity especially for low-frequency mutations remains crucial. This study demonstrated superior performance of the newly developed digital PCR (dPCR) kit for ctDNA-based EGFR p.T790M detection in metastatic non-small-ce...

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Detalles Bibliográficos
Autores principales: Xu, Jiachen, Wu, Wei, Wu, Chunyan, Mao, Yong, Qi, Xiaowei, Guo, Lin, Lu, Renquan, Xie, Shuhong, Lou, Jiatao, Zhang, Yu, Ding, Yiyan, Guo, Zijian, Zhang, Li, Liang, Naixin, Chen, Peng, Zhang, Cuicui, Tao, Min, Yu, Zhengyuan, Geng, Hua, Xu, Meilin, Shi, Meiqi, Wang, Li, Guo, Wei, Zhao, Jun, Li, Jianjie, Shi, Lixia, Zhang, Yan, Qin, Zhonghua, Chen, Jun, Liu, Jinghao, Ren, Jing, Yang, Zhenlin, Pan, Xin, Lv, Zhaoqing, Dong, Hao, Zhang, Jie, Ou, Jiajia, Li, Zhaoliang, Kaji, Kavanaugh, Wang, Yan, Wang, Jie, Wang, Zhijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577974/
https://www.ncbi.nlm.nih.gov/pubmed/34858779
http://dx.doi.org/10.21037/tlcr-21-564

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