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Novel tensorial Thixo-Visco-Plastic framework for rheological characterization of human blood

Characterizing human blood, a complex material with a spectrum of thixo-elasto-visco-plastic properties, through the development of more effective and efficient models has achieved special interest of late. This effort details the development a new approach, the tensorial-enhanced-Thixo-Visco-Plasti...

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Detalles Bibliográficos
Autores principales: Pincot, André, Armstrong, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578634/
https://www.ncbi.nlm.nih.gov/pubmed/34754014
http://dx.doi.org/10.1038/s41598-021-01362-8
Descripción
Sumario:Characterizing human blood, a complex material with a spectrum of thixo-elasto-visco-plastic properties, through the development of more effective and efficient models has achieved special interest of late. This effort details the development a new approach, the tensorial-enhanced-Thixo-Visco-Plastic model (t-e-TVP), which integrates elements from the proven Bingham and generalized Maxwell systems to create a more robust framework and subsequently cast into a tensorial format. Here, the elastic and viscoelastic stress contributions from the microstructure are superimposed upon the viscoelastic backbone solution for stress offered by the modified TVP frame. The utility of this novel model is tested against the contemporary tensorial-ethixo-mHAWB (t-ethixo-mHAWB) framework, a similar model with a greater number of parameters, using rheological data of human blood collected on an ARESG2 strain-controlled rheometer. The blood samples are parametrically and statistically analyzed, entailing the comparison of the t-e-TVP and t-ethixo-mHAWB models with their capacity to accurately predict small and large amplitude oscillatory shear as well as unidirectional large amplitude oscillatory shear flow in blood.