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Novel tensorial Thixo-Visco-Plastic framework for rheological characterization of human blood

Characterizing human blood, a complex material with a spectrum of thixo-elasto-visco-plastic properties, through the development of more effective and efficient models has achieved special interest of late. This effort details the development a new approach, the tensorial-enhanced-Thixo-Visco-Plasti...

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Autores principales: Pincot, André, Armstrong, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578634/
https://www.ncbi.nlm.nih.gov/pubmed/34754014
http://dx.doi.org/10.1038/s41598-021-01362-8
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author Pincot, André
Armstrong, Matthew
author_facet Pincot, André
Armstrong, Matthew
author_sort Pincot, André
collection PubMed
description Characterizing human blood, a complex material with a spectrum of thixo-elasto-visco-plastic properties, through the development of more effective and efficient models has achieved special interest of late. This effort details the development a new approach, the tensorial-enhanced-Thixo-Visco-Plastic model (t-e-TVP), which integrates elements from the proven Bingham and generalized Maxwell systems to create a more robust framework and subsequently cast into a tensorial format. Here, the elastic and viscoelastic stress contributions from the microstructure are superimposed upon the viscoelastic backbone solution for stress offered by the modified TVP frame. The utility of this novel model is tested against the contemporary tensorial-ethixo-mHAWB (t-ethixo-mHAWB) framework, a similar model with a greater number of parameters, using rheological data of human blood collected on an ARESG2 strain-controlled rheometer. The blood samples are parametrically and statistically analyzed, entailing the comparison of the t-e-TVP and t-ethixo-mHAWB models with their capacity to accurately predict small and large amplitude oscillatory shear as well as unidirectional large amplitude oscillatory shear flow in blood.
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spelling pubmed-85786342021-11-10 Novel tensorial Thixo-Visco-Plastic framework for rheological characterization of human blood Pincot, André Armstrong, Matthew Sci Rep Article Characterizing human blood, a complex material with a spectrum of thixo-elasto-visco-plastic properties, through the development of more effective and efficient models has achieved special interest of late. This effort details the development a new approach, the tensorial-enhanced-Thixo-Visco-Plastic model (t-e-TVP), which integrates elements from the proven Bingham and generalized Maxwell systems to create a more robust framework and subsequently cast into a tensorial format. Here, the elastic and viscoelastic stress contributions from the microstructure are superimposed upon the viscoelastic backbone solution for stress offered by the modified TVP frame. The utility of this novel model is tested against the contemporary tensorial-ethixo-mHAWB (t-ethixo-mHAWB) framework, a similar model with a greater number of parameters, using rheological data of human blood collected on an ARESG2 strain-controlled rheometer. The blood samples are parametrically and statistically analyzed, entailing the comparison of the t-e-TVP and t-ethixo-mHAWB models with their capacity to accurately predict small and large amplitude oscillatory shear as well as unidirectional large amplitude oscillatory shear flow in blood. Nature Publishing Group UK 2021-11-09 /pmc/articles/PMC8578634/ /pubmed/34754014 http://dx.doi.org/10.1038/s41598-021-01362-8 Text en © This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Pincot, André
Armstrong, Matthew
Novel tensorial Thixo-Visco-Plastic framework for rheological characterization of human blood
title Novel tensorial Thixo-Visco-Plastic framework for rheological characterization of human blood
title_full Novel tensorial Thixo-Visco-Plastic framework for rheological characterization of human blood
title_fullStr Novel tensorial Thixo-Visco-Plastic framework for rheological characterization of human blood
title_full_unstemmed Novel tensorial Thixo-Visco-Plastic framework for rheological characterization of human blood
title_short Novel tensorial Thixo-Visco-Plastic framework for rheological characterization of human blood
title_sort novel tensorial thixo-visco-plastic framework for rheological characterization of human blood
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578634/
https://www.ncbi.nlm.nih.gov/pubmed/34754014
http://dx.doi.org/10.1038/s41598-021-01362-8
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