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Co-evolution based machine-learning for predicting functional interactions between human genes

Over the next decade, more than a million eukaryotic species are expected to be fully sequenced. This has the potential to improve our understanding of genotype and phenotype crosstalk, gene function and interactions, and answer evolutionary questions. Here, we develop a machine-learning approach fo...

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Detalles Bibliográficos
Autores principales: Stupp, Doron, Sharon, Elad, Bloch, Idit, Zitnik, Marinka, Zuk, Or, Tabach, Yuval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578642/
https://www.ncbi.nlm.nih.gov/pubmed/34753957
http://dx.doi.org/10.1038/s41467-021-26792-w