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Extracellular vesicles from hypoxia-preconditioned microglia promote angiogenesis and repress apoptosis in stroke mice via the TGF-β/Smad2/3 pathway

Systemic transplantation of oxygen−glucose deprivation (OGD)-preconditioned primary microglia enhances neurological recovery in rodent stroke models, albeit the underlying mechanisms have not been sufficiently addressed. Herein, we analyzed whether or not extracellular vesicles (EVs) derived from su...

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Detalles Bibliográficos
Autores principales:	Zhang, Lin, Wei, Wei, Ai, Xiaoyu, Kilic, Ertugrul, Hermann, Dirk M., Venkataramani, Vivek, Bähr, Mathias, Doeppner, Thorsten R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578653/ https://www.ncbi.nlm.nih.gov/pubmed/34753919 http://dx.doi.org/10.1038/s41419-021-04363-7

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