Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription

The ARID1A subunit of SWI/SNF chromatin remodeling complexes is a potent tumor suppressor. Here, a degron is applied to detect rapid loss of chromatin accessibility at thousands of loci where ARID1A acts to generate accessible minidomains of nucleosomes. Loss of ARID1A also results in the redistribu...

Descripción completa

Detalles Bibliográficos
Autores principales: Blümli, Seraina, Wiechens, Nicola, Wu, Meng-Ying, Singh, Vijender, Gierlinski, Marek, Schweikert, Gabriele, Gilbert, Nick, Naughton, Catherine, Sundaramoorthy, Ramasubramanian, Varghese, Joby, Gourlay, Robert, Soares, Renata, Clark, David, Owen-Hughes, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578704/
https://www.ncbi.nlm.nih.gov/pubmed/34731603
http://dx.doi.org/10.1016/j.celrep.2021.109943

Ejemplares similares

Ejemplares similares