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Immunological Study of Reconstructed Common Ancestral Sequence of Adenovirus Hexon Protein

Aim: To reconstruct the ancestral sequence of human adenoviral hexon protein by combining sequence variations and structural information. And to provide a candidate hexon protein for developing new adenoviral vector capable of escaping the pre-existing immunity in healthy populations. Methods: The s...

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Detalles Bibliográficos
Autores principales:	Wang, Yingchen, Zhang, Zhe, Shang, Lei, Gao, Hong, Du, Xiqiao, Li, Falong, Gao, Ya, Qi, Guiyun, Guo, Weiyuan, Qu, Zhangyi, Dong, Tuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578728/ https://www.ncbi.nlm.nih.gov/pubmed/34777273 http://dx.doi.org/10.3389/fmicb.2021.717047

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