Blockade of the natriuretic peptide clearance receptor attenuates proteinuria in a mouse model of focal segmental glomerulosclerosis

Glomerular podocytes play a key role in proteinuric diseases. Accumulating evidence suggests that cGMP signaling has podocyte protective effects. The major source of cGMP generation in podocytes is natriuretic peptides. The natriuretic peptide clearance receptor (NPRC) binds and degrades natriuretic...

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Detalles Bibliográficos
Autores principales: Wang, Liming, Tang, Yuping, Buckley, Anne F., Spurney, Robert F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578888/
https://www.ncbi.nlm.nih.gov/pubmed/34755480
http://dx.doi.org/10.14814/phy2.15095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578888/
https://www.ncbi.nlm.nih.gov/pubmed/34755480
http://dx.doi.org/10.14814/phy2.15095

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