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Knockdown of Oligosaccharyltransferase Subunit Ribophorin 1 Induces Endoplasmic-Reticulum-Stress-Dependent Cell Apoptosis in Breast Cancer
Ribophorin 1 (RPN1) is a major part of Oligosaccharyltransferase (OST) complex, which is vital for the N-linked glycosylation. Though it has been verified that the abnormal glycosylation is closely related to the development of breast cancer, the detail role of RPN1 in breast cancer remains unknown....
Autores principales: | Ding, Jiajun, Xu, Jiahui, Deng, Qiaodan, Ma, Wei, Zhang, Rui, He, Xueyan, Liu, Suling, Zhang, Lixing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578895/ https://www.ncbi.nlm.nih.gov/pubmed/34778038 http://dx.doi.org/10.3389/fonc.2021.722624 |
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