Validation of GWAS-Identified Variants for Anti-TNF Drug Response in Rheumatoid Arthritis: A Meta-Analysis of Two Large Cohorts

We aimed to validate the association of 28 GWAS-identified genetic variants for response to TNF inhibitors (TNFi) in a discovery cohort of 1361 rheumatoid arthritis (RA) patients monitored in routine care and ascertained through the REPAIR consortium and DANBIO registry. We genotyped selected marker...

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Detalles Bibliográficos
Autores principales: Sánchez-Maldonado, Jose Manuel, Cáliz, Rafael, López-Nevot, Miguel Ángel, Cabrera-Serrano, Antonio José, Moñiz-Díez, Ana, Canhão, Helena, Ter Horst, Rob, Quartuccio, Luca, Sorensen, Signe B., Glintborg, Bente, Hetland, Merete L., Filipescu, Ileana, Pérez-Pampin, Eva, Conesa-Zamora, Pablo, Swierkot, Jerzy, den Broeder, Alfons A., De Vita, Salvatore, Petersen, Eva Rabing Brix, Li, Yang, Ferrer, Miguel A., Escudero, Alejandro, Netea, Mihai G., Coenen, Marieke J. H., Andersen, Vibeke, Fonseca, João E., Jurado, Manuel, Bogunia-Kubik, Katarzyna, Collantes, Eduardo, Sainz, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579100/
https://www.ncbi.nlm.nih.gov/pubmed/34777329
http://dx.doi.org/10.3389/fimmu.2021.672255

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