CD38 Deficiency Protects Mice from High Fat Diet-Induced Nonalcoholic Fatty Liver Disease through Activating NAD(+)/Sirtuins Signaling Pathways-Mediated Inhibition of Lipid Accumulation and Oxidative Stress in Hepatocytes

Nonalcoholic fatty liver disease (NAFLD) is characterized by excessive lipid accumulation in hepatocytes. CD38 was initially identified as a lymphocyte surface antigen and then has been found to exist in a variety of cell types. Our previous studies showed that CD38(-/-) mice were resistant to high-...

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Detalles Bibliográficos
Autores principales: Xie, Lin, Wen, Ke, Li, Qian, Huang, Cong-Cong, Zhao, Jia-Le, Zhao, Qi-Hang, Xiao, Yun-Fei, Guan, Xiao-Hui, Qian, Yi-Song, Gan, Lu, Wang, Ling-Fang, Deng, Ke-Yu, Xin, Hong-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579443/
https://www.ncbi.nlm.nih.gov/pubmed/34803499
http://dx.doi.org/10.7150/ijbs.65588

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